Simparica is a prescription medication used to treat and prevent flea and tick infestations in dogs and cats. It is a chewable tablet that is given once a month. Simparica is generally well-tolerated, but some pets may experience side effects.

How Often Do Pets Experience Side Effects from Simparica?

Mild Side Effects

The most common side effects of Simparica are mild and temporary. They may include:

Vomiting

Diarrhea

Lethargy

Loss of appetite

Skin irritation

These side effects typically go away within a few days. If your pet experiences any of these side effects, contact your veterinarian.

Serious Side Effects

In rare cases, Simparica can cause serious side effects. These side effects may include:

Neurological disorders, such as seizures

Liver failure

Kidney failure

Death

These side effects are very rare, but they can be fatal. If your pet experiences any of these side effects, seek immediate veterinary attention.

Risk Factors for Side Effects

Certain pets are at a higher risk of experiencing side effects from Simparica. These pets include:

Puppies and kittens

Pets with a history of liver or kidney disease

Pets that are taking other medications

If your pet is in any of these high-risk groups, talk to your veterinarian about the risks and benefits of Simparica before giving it to your pet.

How to Minimize the Risk of Side Effects

There are a few things you can do to minimize the risk of side effects from Simparica. These include:

Give your pet Simparica exactly as directed by your veterinarian.

Do not give your pet Simparica if they are sick or have a history of liver or kidney disease.

Tell your veterinarian about all of the medications that your pet is taking.

By following these tips, you can help to minimize the risk of side effects from Simparica.